Technical Report XXV
A Bayesian Inference Based Computational Tool for Parametric and Nonparametric Medical Diagnosis
T Chatzimichail, AT Hatjimihail
Abstract
Medical diagnosis is the basis for treatment and management decisions in healthcare. Conventional methods for medical diagnosis commonly use established clinical criteria and fixed numerical thresholds. Such an approach is limited and may fail to capture the intricate relations between diagnostic tests and the varying prevalence of diseases. To explore this further, we have developed a freely available specialized computational tool that employs Bayesian inference to calculate the posterior probability of disease. This novel software comprises three distinct modules, each designed to define and compare parametric and nonparametric distributions effectively. The tool analyzes datasets obtained from two separate diagnostic tests performed on diseased and nondiseased populations. We demonstrate the utility of this software by analyzing fasting plasma glucose and glycated hemoglobin A1c data from the National Health and Nutrition Examination Survey (NHANES). Our results are validated using the oral glucose tolerance test as a reference standard, and we explore both parametric and nonparametric distribution models for the Bayesian diagnosis of diabetes mellitus.
First Published
2023-09-04
Revised
2026-05-26
DOI
Citation
Chatzimichail T, Hatjimihail AT. A Bayesian Inference Based Computational Tool for Parametric and Nonparametric Medical Diagnosis. Technical Report XXV. Hellenic Complex Systems Laboratory; 2023. https://doi.org/10.5281/zenodo.20393633.
Source Notebook (Revised on 2026-05-06)
About Publication Dates
Please refer to HCSL Technical Reports Publication Dates Policy.
Terms of Use
The material made freely available by Hellenic Complex Systems Laboratory is subject to its Terms of Use.